A case of Churg-Strauss syndrome: flow cytometric analysis of the surface activation markers of peripheral eosinophils.

© 2013 The Authors. doi: 10.2340/00015555-1384 Journal Compilation © 2013 Acta Dermato-Venereologica. ISSN 0001-5555 Churg–Strauss syndrome (CSS) is a complex multiple organ disease (1). The American College of Rheumatology has proposed 6 criteria for CSS classification, with the fulfilment of 4 criteria making a diagnosis of CSS (2). These criteria include asthma, eosinophilia, mononeuropathy or polyneuropathy, pulmonary infiltrates, paranasal sinus abnormality and extravascular eosinophils. Cutaneous manifestations are frequently observed in 40% of CSS patients. We report here a case of CSS presenting atypical cutaneous and subcutaneous manifestations of CSS with flow cytometric analysis of the peripheral eosinophils.